MT SBIR/STTR Matching Grant

The goal of this program is to support collaborative translational research projects aligned with NIH efforts to enhance the translation of basic biological discoveries into clinical applications that improve health. It encourages high quality science demonstrating the potential to result in understanding an important disease process or lead to new therapeutic interventions, diagnostics, or prevention strategies within the research interests and priorities of the participating NIH Institutes/Centers (ICs).Specifically, the program seeks to broaden and strengthen translational research collaborations between basic and clinical researchers both within and outside NIH to accelerate and enhance translational science by promoting partnerships between NIH intramural investigators (e.g., those conducting research within the labs and clinics of the NIH) and extramural investigators (e.g., those conducting research in labs outside the NIH), and by providing support for extramural investigators to take advantage of the unique research opportunities available at the NIH Clinical Center by conducting clinical research projects in collaboration with NIH intramural investigators.

The Commercial Real Estate Acquisition Loan (CREAL) Program provides Philadelphia small business owners with a grant of up to $35,000 for closing costs alongside a mortgage loan of up to $350,000 to purchase commercial property in low- and moderate-income areas. Administered by the City of Philadelphia's Department of Commerce in partnership with the Women's Opportunities Resource Center (WORC), the program is designed to promote asset ownership and help business owners build generational wealth by transitioning from leasing to owning their commercial space. Eligible properties must be located on an approved commercial corridor, and technical assistance is provided throughout the purchase process — both before and after acquisition. The program prioritizes applicants who are unlikely to access traditional lending due to financial barriers. To qualify, applicants must be a business owner with a low-to-moderate income (or own a business located in a low-to-moderate income community), have a credit score of 550 or higher, be registered and licensed with the City of Philadelphia, and be current on city business taxes.

The City of Suffolk offers a Small Business Improvement Grant to local retail and restaurant operations to help them fund building improvements. Businesses can get grants equal to up to 50% of their project costs, not to exceed $10,000. Companies must commit to creating at least one new, full-time job to qualify.

This program by the small business coaching, funding and risk monitoring company Breva offers a $5,000 small business grant every quarter to “an entrepreneur who is having a positive impact in an underrepresented community.” Applicants must have demonstrated that impact through something like job creation, product innovation or improved accessibility.

The New Mexico Small Business Assistance (NMSBA) Program provides New Mexico small businesses facing technical challenges access to the unique expertise and capabilities of Los Alamos and Sandia national laboratories. At no cost to the business, small businesses can seek assistance from lab scientists and engineers to solve challenges and overcome barriers to company success. Since 2000, the two national laboratories have provided $80.6 million in technical assistance to 3,267 businesses enabling 11,116 jobs to be created and retained across the state’s 33 counties.