SC Relentless Challenge Grant
SC Department of Commerce
About the Grant
The South Carolina Department of Commerce provides the Relentless Challenge (RC) Grant Program. This is a statewide competitive scheme that plans to award approximately $1,000,000 for the 2026 funding cycle.
The RC grant funds projects that foster a sustainable innovation ecosystem and that focus on high growth/high impact entrepreneurship, talent development, access to capital, and university/industry collaborations. Matching funds are available up to a maximum of $75,000.
Notes
Note: The 2025 application deadlline has passed but this is an annual program. Check back for more updates on the 2026 application window - typically held during the fall.
Related Grants
2026 National Technical Assistance Programs
Health Resources and Services Administration
The FY 2026 National Technical Assistance Programs (NTAP) cooperative agreement supports three national organizations to develop and deliver technical assistance (TA) to existing and potential health centers with a focus on: Supporting the delivery of comprehensive, high-quality primary health care; improving chronic disease management, nutrition, and preventive services; improving operational effectiveness, efficiency, and quality; addressing emergent public health needs and priorities; complying with and exceeding Health Center Program and supplemental funding requirements.
Fairview URA Grant Program
City of Salem
The City of Salem offers a matching grant program in the Fairview Urban Renewal Area (URA) to support businesses in constructing new buildings, adding to existing structures, or investing in permanent manufacturing equipment and related building improvements. This program is designed to encourage economic growth and enhance business operations within the district. By providing financial support, the program helps reduce the cost burden of construction and equipment investments, making it easier for businesses to grow. For property owners and business tenants, this program offers an opportunity to modernize facilities and improve productivity, benefiting both individual businesses and the community as a whole.
Colorado Springs Downtown Development Grants
City of Colorado Springs
The City of Colorado Springs has multiple grants available for development in their Downtown corridor. Elligible businesses can receive $10,000 - $50,000 as reimbursement for construction and/or improvement costs to downtown buildings.
Mesa Small Business Assistance Program
City of Mesa
A structured component of Mesa Business Builder offering one-on-one consulting, training, and professional advising (digital and in-person support). Supports micro- and underserved businesses through measurable milestones. This program offers free services and grant packages to small businesses in Mesa, AZ. The lifetime cap of these services is $20,000 per business