SC Relentless Challenge Grant
SC Relentless Challenge Grant
SC Department of Commerce
ABOUT THE GRANT
The South Carolina Department of Commerce provides the Relentless Challenge (RC) Grant Program. This is a statewide competitive scheme that plans to award approximately $1,000,000 for the 2026 funding cycle.
The RC grant funds projects that foster a sustainable innovation ecosystem and that focus on high growth/high impact entrepreneurship, talent development, access to capital, and university/industry collaborations. Matching funds are available up to a maximum of $75,000.
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NOTES
Note: The 2025 application deadlline has passed but this is an annual program. Check back for more updates on the 2026 application window - typically held during the fall.
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Other Grants
Motor City Match Grant
Motor City Match
The Motor City Match Cash Track provides Detroit-based businesses with gap funding grants of up to $100,000 to help close a project's financing gap and open a new brick-and-mortar location to the public. Administered by Motor City Match, the Cash Track is open to both new businesses opening their first Detroit location and existing businesses opening an additional Detroit location, with the average grant award totaling $50,000. Grants are need-based and are designed to fill the funding gap remaining after applicants have secured other capital, with the award typically not exceeding 50% of total project costs and requiring at least 10% owner equity. In addition to grant funding, the program supports applicants with financial planning and project management assistance, lender networking events that connect businesses to community lending partners, and facilitated introductions to help applicants close any remaining loan financing they may need. Awardees that open are also promoted through Motor City Match, DEGC, and Detroit Means Business channels, providing additional publicity for the business. Businesses already open and expanding within their current space are not eligible to apply.
Massachusetts Transition and Growth Program
Massachusetts Life Sciences Center
The Massachusetts Transition and Growth Program (MassTAG) is a recruitment tool targeting life sciences companies considering their first presence in Massachusetts. This highly competitive program is designed to attract out-of-state, international, and newly formed companies that meet MLSC’s strategic objectives to become part of the Massachusetts life sciences ecosystem. Successful applicants will receive grant awards based on net new jobs created within the company’s first 12 months of Massachusetts operations, to be paid out retroactively in three annual installments.
VCEDA Telehealth Fund
Virginia Coalfield Economic Development Authority
The VCEDA Telehealth Fund is a grant fund established to help address telehealth and telemedicine needs in the VCEDA region. For-profit and nonprofit entities and industrial or economic development authorities in the VCEDA region are eligible to apply for funds from the VCEDA Telehealth Fund. Available funding is based upon annual appropriation from the Virginia General Assembly. Grant funds provided by VCEDA under this program must be used for initiatives intended to address telehealth and telemedicine needs in the VCEDA region.
RI Food Export Program
Bryant University
Food Export USA–Northeast (Food Export–Northeast) is a nonprofit organization created in 1973 as a cooperative effort between 10 Northeastern state agricultural promotion agencies and the United States Department of Agriculture’s Foreign Agricultural Service (FAS). Export’s goal is to provide a wide range of services to facilitate trade between Northeastern food suppliers and importers around the world. With the Branded Program, you may double your budget with 50% cost reimbursement on: -International website development -Foreign market-compliant packaging and labels -Advertising and public relations -In-store promotions and product demonstrations -Fees for exhibiting at select overseas and domestic trade shows -Marketing and point-of-sale materials -Freight costs for product samples
Integration of Imaging and Fluid-Based Tumor Monitoring in Cancer Therapy
National Institutes of Health
Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) seeks research project (R01) grant applications describing projects that integrate imaging and fluid-based tumor monitoring (liquid biopsy) assays during cancer therapy in patients to determine the optimal use of those modalities in the characterization of therapy response and/or emergence of resistance.