Englewood Business Initiation Grant

This Notice of Funding Opportunity (NOFO) encourages applications for investigator-initiated, early phase, clinical trials of natural products (i.e., botanicals, probiotics, and products marketed as dietary supplements), which have a strong scientific premise to justify further clinical testing. For this NOFO, natural products include promising nutritional regimens that standardize the amount of a specific naturally occurring nutritional compound (e.g., omega-3 fatty acids, anthocyanidins, or polyphenols) and have compelling preliminary evidence. Under this NOFO, trials must be designed so that results, whether positive or negative, will provide information of high scientific utility and will support decisions about further development or testing of the natural product. This NOFO will provide up to three years (R61 phase) of support for milestone-driven testing of pharmacokinetics, bioavailability, and assessment of the natural products effect (i.e., measure of mechanism of action) when used by humans on a specified target measure. If milestones in the R61 phase are achieved, up to 3 years of additional support (R33 phase) may be awarded to replicate the impact of the natural product on target engagement(s) when used by humans and assess whether there is an association between the degree of the impact on the target engagement and clinical outcomes in a participant population. Applications are encouraged to design R33 studies to determine how to optimize the impact of the natural product on the target engagement by optimizing the delivery of the natural product through examination of different doses or formulations. In addition, applications can be designed to combine the natural product with another treatment approach that is known to impact the same target engagement measure; or study the impact of the natural product in a population that is more responsive,

The Electrochemical Systems program is part of the Chemical Process Systems cluster, which also includes: 1) the Catalysis program; 2) the Interfacial Engineering program; and 3) the Process Systems, Reaction Engineering, and Molecular Thermodynamics program. The goal of the Electrochemical Systems program is to support fundamental engineering science research that will enable innovative processes involving electrochemistry or photochemistry for the sustainable production of electricity, fuels, chemicals, and other specialty and commodity products. Processes utilizing electrochemistry or photochemistry for sustainable energy and chemical production must be scalable, environmentally benign, reduce greenhouse gas production, and utilize renewable resources. Research projects that stress fundamental understanding of phenomena that directly impact key barriers to improved system or component-level performance (for example, energy efficiency, product yield, process intensification) are encouraged. Processes for energy storage should address fundamental research barriers for renewable electricity storage applications, for transport propulsion, or for other applications that could have impact towards climate change mitigation. For projects concerning energy storage materials, proposals should involve testable hypotheses that involve device or component performance characteristics that are tied to fundamental understanding of transport, kinetics, or thermodynamics. Advanced chemistries beyond lithium-ion are encouraged. Proposed research on processes utilizing electrochemistry or photochemistry should be inspired by the need for economic and impactful conversion processes. All proposal project descriptions should address how the proposed work, if successful, will improve process realization and economic feasibility and compare the proposed work against current state of the art. Topics of interest include: -Electrochemical energy storage and electrochemical production/conversion systems. -Radically new battery systems that can move the U.S. more rapidly toward a more sustainable transportation future and to greater renewable electricity production penetration. -High-energy density and high-power density batteries suitable for transportation and renewable energy storage applications are of primary interest. -Advanced systems involving metal anodes, solid-state electrolytes, nonaqueous systemsbeyond lithium, aqueous systems beyond lithium,and multivalent chemistries are encouraged. -Novel electrochemical and photochemical systems and processes for the production of chemicals and high-value products are encouraged. Additional fundamental science topics of interest to this program include the study of: -advanced fuel cell systems or fuel cell components for transportation propulsion or grid energy storage applications; -flow batteries for stationary energy storage applications including alternative redox chemistries (e.g., organic, inorganic, organometallic, macromolecular) and operating -strategies (e.g., redox-mediation, suspensions); and -photocatalytic or photoelectrochemical processes and devices for the splitting of water into hydrogen gas or for the reduction of carbon dioxide to liquid or gaseous fuels.

KY Innovation offers comprehensive programs to help companies apply for, win and match federal Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) grants and contracts. The SBIR/STTR programs are known as America's Seed Fund for good reason. They provide a vital source of non-dilutive capital in the form of federal grants and contracts for promising technologies, while allowing innovators to maintain intellectual property and positioning them well to receive private follow on funding. KY Innovation can be a key partner in helping you compete. Innovators that receive SBIR or STTR awards can benefit from additional funding to bridge the gap between Phase I and Phase II, as well as to speed up the commercialization process. The Kentucky SBIR/STTR Matching Funds Award Program is a non-dilutive, reimbursable grant, awarded on a competitive basis. The grant will match up to $100,000 for a Phase I project, and up to $150,000 for a phase two project. Applicants must be recipients of a SBIR/STTR award, a for-profit company, and based in, or willing to re-locate to, Kentucky.

The Agricultural Products Utilization Commission (APUC) creates new wealth through the development of new and expanded uses of North Dakota's agricultural products through a grant program. The first 15 qualifying applicants are invited to present funding proposals on a quarterly basis for the following grant categories: -Basic and Applied Research -Marketing and Utilization -Farm Diversification -Technical Assistance -Nature Based Agri-Tourism -Prototype Development and Technology

Eligible businesses can receive up to $10,000 per year to reimburse 50% of the expenses they incur while expanding their export sales. Businesses must be for-profit, have an exportable product or service and be in operation for at least a year (among other requirements) in order to be eligible for this grant.