Inspiring Spring Mountain: Corridor Improvement Grant

This Notice of Funding Opportunity (NOFO) encourages applications for investigator-initiated, early phase, clinical trials of natural products (i.e., botanicals, probiotics, and products marketed as dietary supplements), which have a strong scientific premise to justify further clinical testing. For this NOFO, natural products include promising nutritional regimens that standardize the amount of a specific naturally occurring nutritional compound (e.g., omega-3 fatty acids, anthocyanidins, or polyphenols) and have compelling preliminary evidence. Under this NOFO, trials must be designed so that results, whether positive or negative, will provide information of high scientific utility and will support decisions about further development or testing of the natural product. This NOFO will provide up to three years (R61 phase) of support for milestone-driven testing of pharmacokinetics, bioavailability, and assessment of the natural products effect (i.e., measure of mechanism of action) when used by humans on a specified target measure. If milestones in the R61 phase are achieved, up to 3 years of additional support (R33 phase) may be awarded to replicate the impact of the natural product on target engagement(s) when used by humans and assess whether there is an association between the degree of the impact on the target engagement and clinical outcomes in a participant population. Applications are encouraged to design R33 studies to determine how to optimize the impact of the natural product on the target engagement by optimizing the delivery of the natural product through examination of different doses or formulations. In addition, applications can be designed to combine the natural product with another treatment approach that is known to impact the same target engagement measure; or study the impact of the natural product in a population that is more responsive,

digitalundivided's BREAKTHROUGH Program, sponsored by JPMorgan Chase & Co, provides founders with a deeper understanding of their customers, startup funding, growth marketing strategies, and networking opportunities to scale their ventures. Each company accepted into the program will receive a $5,000 grant.

This Notice of Funding Opportunity Announcement (NOFO) solicits resource grant applications for projects that will provide accurate, useful, usable, and understandable health information to populations that experience health disparities and their health care providers. This NOFO supports the development of resources that can be used to improve health and well-being and that lead to reductions in health disparities. Access to accurate, useful, usable, and understandable health information is an important factor when managing health and health care. Proposed projects should harness the capabilities of information technology and medical or health libraries to disseminate clear, evidence-based health-related information in formats used by individuals and their health care providers. Proposed projects should emphasize the development and deployment of new information resources or services, or expand and improve an existing resource or service, to meet the needs of populations experiencing health disparities and to promote health access for all.

The Venture Pitch assistance micro-grant can reimburse up to $5000, spent on hiring an independent, third party to assist in the creation of an investor pitch deck, assemble a researched list of at least 5 investors to contact that includes the investor profile, the investment criteria, their portfolio, news releases of companies they invested in and create an advanced and well thought out financial and P&L model with market size, costs, pricing, sales key assumptions. To be eligible for this grant, applicants must have received a Phase I or Phase II SBIR/STTR award.

The Modernization Investment Support Initiative (MISI) Program gives grants to eligible Delaware businesses that need help modernizing their operations to remain competitive. Eligible businesses can get up to 20% of approved modernization expenses reimbursed, up to $1 million per project. Businesses can use the funds toward equipment and machinery purchases, construction, and engineering services. In order to qualify, businesses need to have an operating history of at least ten years, have a proposed modernization budget of at least $1 million, and demonstrate a need for updates to remain competitive.