Philadelphia Quality Jobs Grant

This Notice of Funding Opportunity (NOFO) encourages applications for investigator-initiated mid-phase clinical trials of natural products(i.e., botanicals, dietary supplements, and probiotics), which have a strong scientific premise to justify further clinical testing. For this NOFO, natural products include promising nutritional regimens that standardize the amount of a specific naturally occurring nutritional compound (e.g., omega-3 fatty acids, anthocyanidins, or polyphenols) and have compelling preliminary evidence. All applications submitted under this NOFO must be supported by sufficient preliminary data demonstrating bioavailability (if applicable) and documentation that the natural product produces a reproducible and measurable impact on target engagement (i.e., measure of the mechanism of action). Only in cases when it is not possible/practical to measure target engagement in the patient population of interest or when there is a fundamental understanding of the products mechanism of action will this preliminary data requirement be waived. Applications submitted to this NOFO should propose a mid-phase clinical trial to do the following: determine the optimal dose or formulation of a given natural product for use in a future multi-site efficacy trial; or determine which patient phenotypes will be responders versus non-responders to the natural product to inform inclusion/exclusion criteria of a future efficacy trial. Clinical trials submitted under this NOFO are expected to be hypothesis based, milestone-driven, and directly related to the research priorities and mission of NCCIH. This NOFO will not support single-site or multi-site efficacy or effectiveness trials, nor will it support trials to test natural products for the treatment or prevention of cancer. Applicants are encouraged to contact the appropriate NCCIH Scientific/Research contact for the area of science for which they are planning to develop an application prior to submitting to this NO

This relaunch of the Atlantic City Revitalization Program (“Program”) will continue to facilitate Atlantic City’s effective utilization of allocated funds for community-driven capital projects. The goal of this Program is to proactively address the negative economic impacts of the pandemic by investing in projects that demonstrate an ability to cultivate the environment and neighborhoods necessary to attract and retain a local workforce, enable business creation and tourism, enhance downtown vitality through small business support efforts, support clean and safe initiatives, address food insecurity issues, and buttress social impact supports for the community at large. Administered by the Authority, this Program will support real estate development, specifically capital projects (each, a “Project”) in the form of Grants, to support rehabilitation or new construction, as well as other development costs associated with an award between $250,000 and a maximum award of $2.5 million in grant funding to one Project. This will then meet the requirement of “Investing in Communities” by providing funding to activate underutilized properties for community focused investments and to activate projects that will catalyze new business sectors in NJ, support communities, and improve the business community within Atlantic City. This grant will improve investment in communities by working to activate underutilized, distressed, or vacant land for projects in order to promote equitable economic growth and community wealth building in Atlantic City.

This Notice of Funding Opportunity Announcement (NOFO) is designed to encourage and facilitate the entry of investigators to the area of brain imaging research. This NOFO will support both newly independent investigators and established investigators who are seeking to develop and adopt neuroimaging tools and methodologies in their research programs and conduct small "proof-of-concept" studies relevant to substance use disorders and addiction. This NOFO is intended to support Small Research Grant (R03) projects that can be carried out in a short period of time with limited resources.

This program provides grants of up to $10,000 to small businesses damaged by a fire that is no fault of their own. Grants to eligible businesses are available on a first-come-first-serve basis, based on fund availability.

The ROI Jamestown (Reinvestment for Opportunity & Impact) Grant Program provides Jamestown, New York commercial property owners and tenants with reimbursement grants of up to $50,000 to make improvements to their facilities and operations. Administered by the City of Jamestown's Department of Development and funded through federal Community Development Block Grant (CDBG) dollars from the U.S. Department of Housing and Urban Development, the program is designed to facilitate the revitalization of Jamestown's commercial buildings and businesses, encourage economic growth, secure private investment, promote small businesses and entrepreneurship, and ultimately sustain and create jobs. The program is competitive, with grants awarded on a quarterly basis as funding permits. Grant funds may be used for building improvements, permanently installed fixtures and equipment, permanently affixed signage, ADA accessibility improvements, and interior commercial buildouts. Eligible improvements include painting, exterior refinishing, doors, windows, lighting, roof repair, brick repointing, HVAC, handicap-accessible improvements to restrooms, entrances, and ramps, and machinery permanently affixed to the building (available only when the applicant is both the deeded property owner and the business owner). A portion of grant funds may be used for building acquisition on a case-by-case basis, subject to strict job creation requirements. Residential rental buildings (unless connected to a mixed-use building), home-based businesses, financial institutions, nationally dominant chains and franchises, and structures outside Jamestown city limits are not eligible. To qualify, the property must be located within the City of Jamestown's census tracts and be found code-compliant by the City's Building and Code Enforcement Officer, and all City and School taxes and Board of Public Utilities (BPU) accounts must be paid in full. Property owners must provide a copy of their deed, and tenants must provide their lease agreement. Priority is given to commercial buildings in the Downtown Business District, City corridors, and industrial buildings occupied by businesses that will maintain or create employment. Applicants must demonstrate financial viability by providing 12-month and 3-year cash flow projections, or a Profit and Loss statement covering the last two years. Grant recipients must commit to remaining in the location for at least three years for grants of $15,000 or less, and at least five years for larger awards. Business tenants must document these commitments in a signed lease. All applications must include two sets of estimates for the work to be completed, and all estimates involving labor over $2,000 must include prevailing wage. Applicants are also required to self-certify that they are in good standing with the Department of Labor and Department of Environmental Protection. Deeded property owners who receive grant funding must sign a Five-Year Anti-Speculation Agreement, which is recorded as a lien with the Chautauqua County Clerk's Office; if the property is sold within five years of the last grant disbursement, a portion of the grant must be repaid (with the repayment amount decreasing each year). Buildings located in the Downtown Historic District or with an individual historic designation must obtain a No Adverse Effect letter from the State Historic Preservation Office before any work begins. Grant funds may be disbursed either as reimbursement to the applicant for paid invoices, or paid directly to the contractor through a signed Contractor's Agreement.