SD Proof of Concept Program

This Notice of Funding Opportunity (NOFO) is issued by the Food and Drug Administration (FDA), Center for Veterinary Medicine (CVM), and solicits Research Project (R01) grant applications from institutions or organizations that propose to develop or support the development of designated new animal drugs intended for minor uses in major species or for use in minor species (MUMS). The FDA is authorized to provide grants to assist in defraying the costs of qualified safety and effectiveness testing that could be used to satisfy the requirements for FDA approval of MUMS-designated drugs. Only entities developing drugs for veterinary use or parties working as research partners with such entities are eligible for grants. The organization (or applicant) seeking approval of the new animal drug under investigation must have opened an Investigational New Animal Drug (INAD) file with FDA/CVM and must hold a minor use or minor species "designation" granted by FDA/CVM's Office of Minor Use and Minor Species Animal Drug Development (OMUMS) for that drug for a specified intended use, in accordance with the provisions of section 573 of the Food, Drug and Cosmetic Act (21 U.S.C. 360ccc-2) and 21 CFR part 516.

The Affordable Commercial Tenanting (ACT) Grant provides Portland property owners and small business owners with reimbursement grants of up to $300,000 to fund tenant improvements, space related soft costs, and permitting support needed to ready a commercial space for opening. Administered by Prosper Portland, the city's economic development agency, the program is designed to facilitate access to affordable commercial space and support inclusive small business growth by helping local entrepreneurs move into ground floor storefronts at a lower cost. The grant is currently available for properties located within the Interstate Corridor and Gateway Regional Center Tax Increment Finance (TIF) Districts, though the program may expand to other areas of the city in the future. To qualify, the property owner must agree to provide the small business with a minimum three year lease that includes at least one of the following: a lease rate 10 to 25 percent below market, a period of rent abatement, or capped rent escalations during the affordable rate period. The property must be ground floor and zoned for commercial or mixed use. Eligible business owners must demonstrate at least two years of business experience and meet criteria related to displacement, limited access to capital, first generation business ownership, or location within a low income census tract. Funds may be used for hard costs to ready the space (such as standard finishes, signage, landscaping, lighting, and security upgrades), up to $25,000 for soft costs like design and permitting fees, and up to $25,000 for predevelopment work. Operating expenses, inventory, and non permanent fixtures are not eligible. Property management companies, mobile businesses, e-commerce businesses, and cannabis businesses are not eligible to apply.

The Kansas Department of Commerce and Kansas Office of Registered Apprenticeship (KOA) has realized significant growth in high-wage and high-demand occupations, but there still remains a significant need to engage small businesses essential to the state economic success. This grant specifically targets small businesses with less than 10 full-time employees, and will provide $7,000 one-time grants to support the registration of New Apprentices in high-wage and high-demand occupations.

The Seattle Back to Business Program provides Seattle small businesses with reimbursement grants to recover from vandalism and property damage and to invest in preventive security measures. Administered by the Seattle Office of Economic Development (OED) , the program builds on the original Storefront Repair Fund (which ran from 2022 to 2024) and consolidates two. The first grant pathway is the Storefront Repair Fund, which reimburses up to $3,000 per incident for the cost of repairing storefront property damage such as broken doors, locks, fences, gates, signs, and windows; businesses may apply for up to three separate incidents that occurred on or after July 1, 2024. The second is the Storefront Security Fund, which provides a one-time reimbursement of up to $6,000 to fund preventive security improvements such as window or door reinforcement, locks, signs, security window film, and shatterproof glass; applicants must first complete a Crime Prevention Through Environmental Design (CPTED) security assessment with a certified expert, and only purchases made after that assessment qualify. Both grants operate as reimbursements, meaning eligible expenses must be paid before applying. To qualify, businesses must be independently owned and non-chain, located within Seattle city limits, have no more than 50 full-time equivalent employees and no more than three locations, generate between $1,000 and $7 million in annual net revenue, and have been in operation for at least 12 months. Priority is given to small businesses owned by people of color, women-owned businesses, and businesses located in highly distressed census tracts. Graffiti removal, security cameras, and loss of stolen goods are not eligible expenses under either fund.

The Cannabis Business Assistance Loan/Grant Fund (CBAF) is a financing resource operated by the Maryland Department of Commerce (Commerce), to provide grants and loans for small businesses, including small, minority-owned and small women-owned businesses entering the adult-use cannabis industry. CBAF may also provide grants to Historically Black Colleges and Universities (HBCUs) for cannabis-related programs and to business development organizations, including incubators, to train and assist small businesses, including minority and women business owners and entrepreneurs, seeking to become licensed to participate in the adult-use cannabis industry.