Small R01s for Clinical Trials Targeting Diseases within the Mission of NIDDK

The FY 2026 National Technical Assistance Programs (NTAP) cooperative agreement supports three national organizations to develop and deliver technical assistance (TA) to existing and potential health centers with a focus on: Supporting the delivery of comprehensive, high-quality primary health care; improving chronic disease management, nutrition, and preventive services; improving operational effectiveness, efficiency, and quality; addressing emergent public health needs and priorities; complying with and exceeding Health Center Program and supplemental funding requirements.

ACCELERATE is focused on solutions that have shown progress in improving access, equity, and integration of oral health or overall health, including for underserved populations. As part of ACCELERATE, companies may receive: -Up to $100,000 in non-dilutive funds, which must be matched directly or in-kind by an industry partner -Support to scope the project and drive toward outcomes -Data and analytics support, including claims analysis, outcomes design, ROI modeling, and more -Networking at closed-door and industry events with our ecosystem of partners -Follow-on support after successful pilots, such as further partnership or investment

Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) intends to stimulate translation of scientific discoveries and engineering developments in imaging, data science and/or spectroscopic technologies into methods or tools that address contemporary problems in understanding the fundamental biology, potential risk of development, diagnosis, treatment, and/or disease status for cancer or other disease.

Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) intends to stimulate efforts to translate scientific discoveries and engineering developments into methods or tools that address problems in basic research to understand disease, or in applied research to assess risk, detect, prevent, diagnose, treat, and/or manage disease. The rationale is to deliver new capabilities to meet evolving requirements for technologies and methods relevant to the advance of research and delivery of care in pre-clinical, clinical and non-clinical settings, domestic or foreign, for conditions and diseases within the missions of participating institutes.

This Funding Opportunity Announcement (FOA) invites applications for centers to support transdisciplinary teams of clinical and mental health services researchers, behavioral scientists, social scientists, health information and communications technologists, health systems engineers, decision scientists, and mental health stakeholders (e.g., service users, family members, clinicians, payers) to engage in high-impact studies that will significantly advance clinical practice and generate knowledge that will fuel transformation of mental health care in the United States. Advanced Laboratories for Accelerating the Reach and Impact of Treatments for Youth and Adults with Mental Illness (ALACRITY) Research Centers will support the rapid development, testing, and refinement of novel and integrative approaches for (1) optimizing the effectiveness of therapeutic or preventive interventions for mental disorders within well-defined target populations; (2) organizing and delivering optimized mental health services within real world treatment settings; and (3) continuously improving the quality, impact, and durability of optimized interventions and service delivery within diverse care systems. The ALACRITY Centers program is intended to support research that maximizes synergies across various components of the mental health research ecosystem, including new discoveries in clinical research, transformative health care technologies, advances in information science, and new federal and state mechanisms for organizing mental health care.