Springfield Small Business Assistance Program

Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) seeks research project (R01) grant applications describing projects that integrate imaging and fluid-based tumor monitoring (liquid biopsy) assays during cancer therapy in patients to determine the optimal use of those modalities in the characterization of therapy response and/or emergence of resistance.

The City of Pasadena’s Economic Development Division has established the Microenterprise Recovery Grant Program to assist local, low- to moderate-income microenterprises —businesses with five or fewer employees —impacted by the 2025 Eaton wildfire and windstorm. Eligible businesses may apply for reimbursement-based grants of up to $5,000 to support stabilization and recovery efforts. To qualify, businesses must operate a brick-and-mortar location within Pasadena city limits, hold a current City business license, employ no more than a total of five employees, and have an owner with income below 80% of the area median income who has experienced economic hardship due to the fires or windstorms.

A grant program for artistic and cultural projects in the city of Seattle. As a small awards program, smART Ventures encourages innovation and widens cultural participation, particularly by individuals, organizations, and communities that may not qualify for other funding programs. Accepting applications year-round, smART Ventures is flexible, inclusive and simple. It provides support ranging from $500 to $1,500, proving that small investments can have big impacts.

This Notice of Funding Opportunity (NOFO) encourages applications for investigator-initiated, early phase, clinical trials of natural products (i.e., botanicals, dietary supplements, and probiotics), which have a strong scientific premise to justify further clinical testing. For this NOFO, natural products include promising nutritional regimens that standardize the amount of a specific naturally occurring nutritional compound (e.g., omega-3 fatty acids, anthocyanidins, or polyphenols) and have compelling preliminary evidence. Under this NOFO, trials must be designed so that results, whether positive or negative, will provide information of high scientific utility and will support decisions about further development or testing of the natural product. This NOFO will provide up to 3 years support for studies to replicate the impact of the natural product on target engagement when used by humans, and assess whether there is an association between the degree of the impact on target engagement and functional or clinical outcomes in a patient population. Applications are encouraged to design studies to determine how to optimize the impact of the natural product on target engagement by optimizing the delivery of the natural product through examination of different doses or formulations. In addition, applications can be designed to combine the natural product with another treatment approach that is known to engage the same target; or study the impact of the natural product in a target population that is more responsive. Clinical trials submitted under this NOFO are expected to be hypothesis based, milestone-driven, and directly related to the research priorities and mission of NCCIH. This R33 funding mechanism is intended to accelerate the translation of emerging basic science findings about natural products into early-stage clinical testing to determine whether continued clinical research is warranted. This NOFO will not support efficacy or effectiveness trials, nor will

The KeyBank Foundation is investing $300,000 to support small businesses and commercial property owners located in the city of Rochester’s EMMA and Beechwood neighborhoods. The program will provide grants ranging from $2,500 to $10,000 for capital improvements such as façade upgrades, lighting, signage, interior repairs, accessibility enhancements and safety improvements—projects designed to immediately improve the appearance, functionality and walkability of neighborhood business corridors.