CT Accelerate Grant

This Notice of Funding Opportunity (NOFO) encourages applications for investigator-initiated, early phase, clinical trials of natural products (i.e., botanicals, dietary supplements, and probiotics), which have a strong scientific premise to justify further clinical testing. For this NOFO, natural products include promising nutritional regimens that standardize the amount of a specific naturally occurring nutritional compound (e.g., omega-3 fatty acids, anthocyanidins, or polyphenols) and have compelling preliminary evidence. Under this NOFO, trials must be designed so that results, whether positive or negative, will provide information of high scientific utility and will support decisions about further development or testing of the natural product. This NOFO will provide up to 3 years support for studies to replicate the impact of the natural product on target engagement when used by humans, and assess whether there is an association between the degree of the impact on target engagement and functional or clinical outcomes in a patient population. Applications are encouraged to design studies to determine how to optimize the impact of the natural product on target engagement by optimizing the delivery of the natural product through examination of different doses or formulations. In addition, applications can be designed to combine the natural product with another treatment approach that is known to engage the same target; or study the impact of the natural product in a target population that is more responsive. Clinical trials submitted under this NOFO are expected to be hypothesis based, milestone-driven, and directly related to the research priorities and mission of NCCIH. This R33 funding mechanism is intended to accelerate the translation of emerging basic science findings about natural products into early-stage clinical testing to determine whether continued clinical research is warranted. This NOFO will not support efficacy or effectiveness trials, nor will

The Brooklyn Pitch Competition awards a total of $450,000 in unrestricted grant funding to selected Brooklyn-based businesses, including a $150,000 grand prize and additional finalist awards ranging from $25,000 to $75,000. Administered by the Social Justice Fund (a Joe and Clara Tsai Foundation initiative), the competition is designed for established businesses ready for their next stage of growth and aims to spotlight entrepreneurs who are strengthening Brooklyn's economy, creating jobs, expanding opportunity, and investing in their communities. To be eligible, businesses must be headquartered or primarily operating in Brooklyn, generate between $1 million and $5 million in annual revenue, demonstrate a clear growth strategy and strong potential for expansion, show evidence of innovation, execution capacity, and business momentum, contribute to Brooklyn's economy through job creation, local hiring, community impact, or neighborhood investment, and be prepared to participate in a competitive screening process and a live pitch event if selected as a finalist. In addition to grant funding, selected finalists pitch live at Barclays Center and receive access to investor introductions, capital matchmaking, strategic advisory sessions, and connections to procurement and growth opportunities. Businesses ready to grow, hire, expand their market reach, or deepen their impact in Brooklyn are the program's target applicants.

The City of York Small Business BLOOM Grant Program will award grants up to $1,500 to established small businesses operating and generating revenue in the City of York for a project that will enhance productivity & operations, expand product or service offerings, or otherwise grow to the next level.

The Commercial Corridor Storefront Activation (CCSA) program is helping to revitalize 12 South and West Side business corridors through targeted improvements to underutilized and vacant commercial spaces. Led by the Department of Planning and Development (DPD), the $30.5 million program is offering grants that fund up to 75% of eligible project costs for qualifying small businesses and property owners. In addition to funding for storefront improvements, each corridor has a partner agency and technical service providers to assist with business-related tasks such as marketing, accounting and business planning, as well as project-specific tasks that include design and permitting.

As your company grows and develops, so will your demand for a larger well-trained workforce. Expanding your workforce can be costly, but through the help of WorkOne, you can reduce the cost of hiring and training new employees. WorkOne will reimburse employers up to 50% of new employee wages for on-the-job training. THIS IS NOT A TAX CREDIT. It is an actual check sent to your company for a portion of the trainees’ wages during the training period of up to six months. The training must pay at least $13.50 per hour.