Dallas County Small Business Grant Fund

This Notice of Funding Opportunity (NOFO) encourages applications for investigator-initiated, early phase, clinical trials of natural products (i.e., botanicals, probiotics, and products marketed as dietary supplements), which have a strong scientific premise to justify further clinical testing. For this NOFO, natural products include promising nutritional regimens that standardize the amount of a specific naturally occurring nutritional compound (e.g., omega-3 fatty acids, anthocyanidins, or polyphenols) and have compelling preliminary evidence. Under this NOFO, trials must be designed so that results, whether positive or negative, will provide information of high scientific utility and will support decisions about further development or testing of the natural product. This NOFO will provide up to three years (R61 phase) of support for milestone-driven testing of pharmacokinetics, bioavailability, and assessment of the natural products effect (i.e., measure of mechanism of action) when used by humans on a specified target measure. If milestones in the R61 phase are achieved, up to 3 years of additional support (R33 phase) may be awarded to replicate the impact of the natural product on target engagement(s) when used by humans and assess whether there is an association between the degree of the impact on the target engagement and clinical outcomes in a participant population. Applications are encouraged to design R33 studies to determine how to optimize the impact of the natural product on the target engagement by optimizing the delivery of the natural product through examination of different doses or formulations. In addition, applications can be designed to combine the natural product with another treatment approach that is known to impact the same target engagement measure; or study the impact of the natural product in a population that is more responsive,

Amazon Business is awarding over $250,000 in monetary grants and prizes to support the growth of 15 small businesses. Existing Amazon Business small business customers based in the US with annual revenues of $1 million or less and have made a purchase on Amazon Business within the 12 months preceding May 1, 2025 can apply for a grant.

The Mississippi Gulf Coast Chamber of Commerce and its divisions, including the Biloxi, Gulfport, Long Beach, and Pass Christian Chambers of Commerce, are now accepting applications for their respective Small Business Development Grant programs. Grants, starting at a minimum of $500, will be awarded to Chamber members selected by a judging committee. Elligible businesses include any members of The Mississippi Gulf Coast Chamber of Commerce with fewer than 50 employees.

The Wareham Redevelopment Authority has created the Storefront Renovation Grant Program to support improvements to commercial properties and businesses. The program aims to encourage investment within businesses and improve the appearance and safety of major areas within town. The Storefront Renovation Grant program offers grants of up to $7,500 for upgrades such as signage, landscaping, lighting, painting and exterior repairs. Businesses will contribute 20% of project costs.

The Oklahoma Department of Commerce is offering a jobs program that refunds employers up to 10% of an employee’s net benefit rate for up to 10 years. Applicants in target industries must commit to creating 10 new direct jobs. New jobs are roles in qualifying industries that did not exist in the state in the prior six months. Employer compensation begins at 7% and increases to 10% once all 10 of the new roles are hired.