Romeoville Startup Grant

This Notice of Funding Opportunity (NOFO) encourages grant applications for Animal and Biological Material Resource Centers. These Centers provide support for special colonies of laboratory animals and associated services, as well as other resources such as informatics tools, reagents, cultures (cells, tissues, and organs) and genetic stocks that serve the biomedical research community in a variety of research areas on a local, regional, and national basis. The goal of projects supported by this NOFO is to provide research resources that facilitate optimization and enhancement of scientific rigor, transparency, and experimental reproducibility of biomedical research. Proposed Animal and Biological Material Resource Centers must have broad application to multiple NIH Institutes or Centers (ICs) to align with the ORIP"s NIH-wide mission (https://orip.nih.gov/about-orip). This funding opportunity is designed to support both continuation of existing resources and to develop new ones when appropriate. Of special interest of the announcement is a requirement of the Center"s close coordination with efforts to develop new approach methodologies (NAMs) that complement traditional animal-based research. These include cell culture, organoids, computational models, and microphysiological systems. Applied Research Component should include studies to generate comparative data to increase applicability of NAMs and promote integration of the most predictive human disease models.

The DC Restaurant & Retail Stabilization Grant provides up to $50,000 in financial assistance to small restaurant and retail businesses in Washington, DC that experienced a revenue decline in 2025. Funded by the Office of the Deputy Mayor for Planning and Economic Development (DMPED) and administered by Capital Impact Partners — a local nonprofit community development financial institution — the program is a $3.875 million initiative designed to help brick-and-mortar businesses remain operational and support long-term sustainability. Grant funds may be used to cover occupancy costs and payroll over a six-month grant period. Preference is given to businesses that lost more than 10% of gross revenue in 2025, did not receive prior DMPED funding in 2023–2025, have a positive impact on the local community, and purchase goods or services from the DC, Maryland, or Virginia economy.

The Maryland Community Investment Venture (MCIV) Fund was created to accelerate the adoption of financial innovations that enhance access to capital and financial services for small business owners in low- to moderate-income (LMI) communities. The MCIV Fund provides grant dollars to fintech firms to pilot products and services in partnership with Maryland state-chartered financial institutions.

This grant supports early-stage socio-technical partnerships focused on research data infrastructure ecosystems. The Cyberinfrastructure for Public Access and Open Science (CI PAOS) program within the Office of Advanced Cyberinfrastructure (OAC) aims to catalyze new and transformative socio-technical partnerships supporting research data infrastructure ecosystems across domains through early-stage collaborative activities between cyberinfrastructure researchers, scientists, research computing experts, data management experts, research labs, university libraries, and other communities of practice. The CI PAOS program supports the NSF Public Access Initiative by encouraging innovation across the CI ecosystem to address accessibility, discoverability, reliability, reproducibility, sustainability, and utility of data products in alignment with NSF and national goals for public access and open science. NSF accepts proposals pursuant to this Program Description year-round. From time to time, NSF may also issue Dear Colleague Letters to encourage proposals on special thematic interests and opportunities related to this program.

The Job Development Investment Grant (JDIG) is a performance-based, discretionary incentive program that provides cash grants directly to a company, when the company creates jobs and invests in the state. Grants are awarded only in competitive recruitment or retention situations. JDIG grants hold companies to strict performance targets, but the grants can significantly help offset the cost of locating or expanding a facility in the state. JDIG grant payments are determined using a formula that takes into consideration the new taxes generated by the new jobs that are created. A percentage of those newly generated funds are reimbursed to the awarded company, for the limited term of the grant and as long as the company meets its performance target.