seCTerRise $10,000 Grant

This Notice of Funding Opportunity (NOFO) invites applications that propose to use mouse models to conduct rigorous preclinical testing of drugs or drug combinations currently used for other conditions, as well as investigational drugs at various stages of clinical development, predicted to be efficacious in AD/ADRD. This initiative will also support preclinical testing of repurposable or investigational drug candidates in combination with non-pharmacologic interventions leading to robust translational outcomes. The central goal is to establish robust proof of concept that will enable rational drug repurposing and combination therapy development for the treatment and prevention of AD/ADRD.

The One North Carolina Fund (OneNC) is a discretionary cash-grant program that allows the Governor to respond quickly to competitive job-creation projects. The North Carolina Department of Commerce administers OneNC on behalf of the Governor. Awards are based on the number of jobs created, level of investment, location of the project, economic impact of the project and the importance of the project to the state and region.

Virginia Economic Development Incentive Grants are designed to attract competitive projects to Virginia. Projects must be significant, creating hundreds of jobs in Virginia by relocating headquarters, administrative, or service sector operations to Virginia. Depending on location and wages offered, companies must create between 200 and 400 jobs, ranging from 150 to 200 percent of the local prevailing wage, and meet minimum capital or job investment requirements. Award amounts vary and are calculated based on a return-on-investment analysis, jobs and wages, capital investment, regional unemployment and poverty figures, and more.

The Live Your Dream Awards provide monetary assistance to women who provide the primary source of financial support for their families. It is the cornerstone program of Soroptimist International of the Americas, LiveYourDream.org's sponsoring organization. Each year, more than $3 million in education grants are awarded to over 2,300 women, many of whom have overcome enormous obstacles including poverty, domestic violence, the death of a spouse and/or substance abuse.

The Disability and Rehabilitation Engineering program is part of the Engineering Biology and Health cluster, which also includes: 1) the Biophotonics program; 2) the Biosensing program; 3) the Cellular and Biochemical Engineering program; and 4) the Engineering of Biomedical Systems program. The Disability and Rehabilitation Engineering program supports fundamental engineering research that will improve the quality of life of persons with disabilities through the development of new theories, methodologies, technologies, or devices. Disabilities could be developmental, cognitive, hearing, mobility, visual, selfcare, independent living, or other. Proposed projects must advance knowledge regarding a specific human disability or pathological motion or understanding of injury mechanisms. Research may be supported that is directed toward the characterization, restoration, rehabilitation, and/or substitution of human functional ability or cognition, or to the interaction between persons with disabilities and their environment. Areas of particular interest are neuroengineering, rehabilitation robotics, brain-inspired assistive or rehabilitative systems, theoretical or computational methods, and novel models of functional recovery including the development and application of artificial physiological systems. Emphasis is placed on significant advancement of fundamental engineering knowledge that facilitates transformative outcomes. The DARE Program encourages high-risk/high-reward proposals that surpass incremental technological improvements. The DARE Program also encourages participatory design and the inclusion of trainees with disabilities as part of the proposed research or broader impacts. Innovative proposals outside of the above specific interest areas may be considered. NSF does not support clinical trials; however, feasibility studies involving human volunteers may be supported if appropriate to the project objectives. The development and application of artificial physiological systems that do not model functional recovery and instead improve fundamental understanding of physiological and pathophysiological processes would be appropriate for EBMS. Furthermore, the DARE program does not support proposals having as their central theme commercialization of a product. Small businesses seeking early stage R&D funding for product development are encouraged to contact the NSF SBIR/STTR program in the America's Seed Fund within the Directorate for Technology, Innovation and Partnerships (TIP).