Small Business, Big Dreams: Women in Business Challenge

Data science is an important cross-cutting research approach in the 2022 - 2026 NIDA Strategic Plan and increasing the capacity of experts in addiction related data science is critical. The purpose of this Notice is to facilitate the entry of investigators to the area of addiction-related data science, including newly independent data scientists or established investigators seeking to incorporate novel and cutting-edge data science methodologies into their research programs for the first time. Through this opportunity, investigators will propose to apply emerging data science methods to answer critical questions requiring advanced data analytic strategies. Projects should be small in scale and answer specific research questions or provide preliminary data for a larger scale project. Applicants are encouraged to use existing datasets, follow FAIR principles, and, when applicable, attend to ethical concerns in the conduct of research involving human subjects. Ultimately, the aim is to expedite the development of robust research programs focused on the convergence of innovative data science techniques and addiction research, with initial projects serving as precursors for subsequent, more expansive research projects.

Summary: Supports promising research that has high potential to lead to or make breakthroughs in breast cancer. All applications must address at least one of the fiscal year 2025 (FY25) Breast Cancer Research Program (BCRP) overarching challenges, unless adequate justification for exception is provided. Applications must address the challenge in a way that can lead to or make a breakthrough and have major impact. The FY25 Breakthrough Award mechanism contains three different funding levels designed to support major (but not all) stages of research that will lead to clinical application. Each level has a defined research scope. The current program announcement discusses the Breakthrough Award Levels 1 and 2. Distinctive Features: · This funding mechanism allows for applications submitted under Funding Level 1 or Funding Level 2. Funding Level 2 also includes a Population Science and Prevention Studies option. With compelling justification, population science and prevention studies may request higher levels of funding and an additional year in the period of performance. · This funding mechanism allows for a single Principal Investigator (PI), or two partnering PIs referred to as the Initiating PI and the Partnering PI. For the Partnering PI Option (PPIO), only the Initiating PI will submit a pre-application, but both PIs will need to submit at the full application stage.

Summary: Supports research that expands or modifies current thinking about and/or approaches in ovarian cancer, exploring innovative concepts or theories in ovarian cancer that could ultimately lead to critical discoveries or major advancements that will drive the field forward. Distinctive Features: Innovation is key. Research projects that demonstrate exceptional scientific merit but lack innovation do not meet the intent of the mechanism. Preliminary data are not required but are allowed for this mechanism. Research projects may focus on any phase of research, from basic laboratory research through translational research, excluding clinical trials.

Since 2023, The HBCU Founders Initiative (HBCUFI) and the United Negro College Fund (UNCF), a philanthropic organization that funds scholarships for Black students and 37 HBCUs, have partnered together to host the Better Futures pitch competition. Better Futures is a national showcase of the entrepreneurial excellence booming out of the nation's 100+ HBCUs. The competition features startups led by HBCU students and alumni from the HBCUFI network who are building innovative solutions and creating better futures. The Better Futures pitch competition has traditionally been held at the National Museum of African American History & Culture in Washington, D.C. with $25,000 in prizes distributed across the top three winners annually.

Summary: The fiscal year 2025 (FY25) Peer Reviewed Cancer Research Program (PRCRP) Idea Award (IA) supports innovative, untested, high-risk/potentially high-reward concepts, theories, paradigms, and/or basic cancer research. The advancement of knowledge in cancer research, patient care, and/or treatment options in the Military Health System (MHS) is critical to active-duty Service Members, Veterans, other military beneficiaries, and the American public. Distinctive Features: • The proposed project should demonstrate creative thinking and innovation. • Incremental advances, the next logical step, or switching a model system from one cancer to another cancer are not appropriate for this award. • Inclusion of preliminary data is not required; however, the project must be based on strong scientific rationale.