WI SBIR Advance

Virginia Economic Development Incentive Grants are designed to attract competitive projects to Virginia. Projects must be significant, creating hundreds of jobs in Virginia by relocating headquarters, administrative, or service sector operations to Virginia. Depending on location and wages offered, companies must create between 200 and 400 jobs, ranging from 150 to 200 percent of the local prevailing wage, and meet minimum capital or job investment requirements. Award amounts vary and are calculated based on a return-on-investment analysis, jobs and wages, capital investment, regional unemployment and poverty figures, and more.

This Notice of Funding Opportunity (NOFO) encourages applications for investigator-initiated mid-phase clinical trials of natural products(i.e., botanicals, dietary supplements, and probiotics), which have a strong scientific premise to justify further clinical testing. For this NOFO, natural products include promising nutritional regimens that standardize the amount of a specific naturally occurring nutritional compound (e.g., omega-3 fatty acids, anthocyanidins, or polyphenols) and have compelling preliminary evidence. All applications submitted under this NOFO must be supported by sufficient preliminary data demonstrating bioavailability (if applicable) and documentation that the natural product produces a reproducible and measurable impact on target engagement (i.e., measure of the mechanism of action). Only in cases when it is not possible/practical to measure target engagement in the patient population of interest or when there is a fundamental understanding of the products mechanism of action will this preliminary data requirement be waived. Applications submitted to this NOFO should propose a mid-phase clinical trial to do the following: determine the optimal dose or formulation of a given natural product for use in a future multi-site efficacy trial; or determine which patient phenotypes will be responders versus non-responders to the natural product to inform inclusion/exclusion criteria of a future efficacy trial. Clinical trials submitted under this NOFO are expected to be hypothesis based, milestone-driven, and directly related to the research priorities and mission of NCCIH. This NOFO will not support single-site or multi-site efficacy or effectiveness trials, nor will it support trials to test natural products for the treatment or prevention of cancer. Applicants are encouraged to contact the appropriate NCCIH Scientific/Research contact for the area of science for which they are planning to develop an application prior to submitting to this NO

The Rural and Agriculture Energy Assistance Program offers grants to farms, ranches, and rural small businesses to help cover the costs of energy audits. Audits are performed by approved assessors who review energy use, as well as buildings, processes, and equipment. The goal is to find ways to be more energy efficient. The grant program covers 75% of the audit expense, with applicants paying the remaining 25% of the costs. Energy assessment costs vary depending on size and scope but typically range between $4,000 and $8,500.

The BMO Celebrating Women grant program was launched as a way to ensure that women-owned businesses received the resources and attention they needed to thrive. Since its inaugural year, the grant has supported a multitude of women-owned businesses across Canada, and within various sectors and industries. The BMO Celebrating Women Grant Program is open to small businesses that are at least 51% women-owned. Additional eligibility requirements include that your business must have been in operation for at least two years, and your annual revenue cannot exceed $5 million. Fifteen female entrepreneurs will receive $10,000 grants.

The MTI Innovation Funding program fuels groundbreaking ideas with grants, loans, and equity investments. Our seasoned team backs scalable businesses that drive Maine’s growth and diversify our industries. Funding amounts range from $10,000 to $250,000 depending on eligibility. This program helps cover initial research, prototype development, and commercialization expenses. MTI prioritizes awarding funds to companies in the following sectors: biotechnology, aquaculture & marine technology, composite materials, environmental technologies, advanced forestry/agriculture technologies, manufacturing, and information technology.